Research in the lab is focused on decoding the molecular basis of transmembrane signaling and transport.
The particular systems we study lie at the intersection of human health and protein science.
We utilize a broad range of methods in structural biology, protein biophysics, pharmacology, and protein engineering to understand how cells recognize and respond to their extracellular environment and maintain intracellular homeostasis.
Recent Posts
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We recently published “The Role of Ligands on the Equilibria Between Functional States of a G Protein-Coupled Receptor” in Journal of the American Chemical S...
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We recently published “Structure of active β-arrestin-1 bound to a G-protein-coupled receptor phosphopeptide” in Nature.
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We recently published “The Dynamic Process of β2-Adrenergic Receptor Activation” in Cell.
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We recently published “Role of Detergents in Conformational Exchange of a G Protein-coupled Receptor” in Journal of Biological Chemistry.
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We recently published “A New Class of Amphiphiles Bearing Rigid Hydrophobic Groups for Solubilization and Stabilization of Membrane Proteins” in Chemistry – ...